NIST SP 800-66

NIST SP 800-66 provides guidance for HIPAA-covered entities on implementing the Security Rule to protect electronic protected health information (ePHI).

It translates HIPAA’s security requirements into practical cybersecurity controls and risk management practices tailored for healthcare organizations.

NIST SP 800-53 Dashboard

SAI360 enables healthcare organizations to manage HIPAA compliance by aligning their cybersecurity practices with the NIST SP 800-66 framework. Our platform centralizes risk assessments, automates control testing, and enforces privacy and security policies that safeguard ePHI.

With SAI360, covered entities can build a defensible compliance program, streamline audits, and protect sensitive patient data from unauthorized access or disclosure.

Modules That Power The Solution

Internal Controls

Reinforce risk mitigation with tested, auditable, and accountable controls.

  • Automate testing and evidence collection
  • Link controls to risks and findings
  • Streamline SOX compliance and audit readiness

IT Risk

Connect cybersecurity, data, and infrastructure risk to enterprise-level oversight.

  • Align with NIST, ISO 27001, and more
  • Assess risks by asset and control
  • Connect IT and enterprise risk teams

Regulatory Compliance

Stay ahead of regulations with real-time compliance oversight.

  • Monitor and implement regulatory changes
  • Map requirements to risks and controls
  • Automate workflows and audit tracking

Policy Management

Centralize and automate your end-to-end policy lifecycle.

  • Streamline creation, approvals, and tracking
  • Link policies to compliance and risk
  • Integrate with training, disclosures, and reporting

Internal Audit

Drive assurance and accountability with streamlined internal audits.

  • Plan and scope audits with confidence
  • Centralize documentation and workflows
  • Track findings through to resolution

Incident Management

Strengthen incident capture and response with automated workflows.

  • Capture all incident types for holistic view
  • Investigate quickly with configurable workflows
  • Correlate trends to risks for proactive action

FAQs

NIST SP 800-66 is a federal guide that helps HIPAA-covered entities implement the HIPAA Security Rule through cybersecurity best practices focused on protecting electronic protected health information (ePHI).

Any healthcare organization, business associate, or covered entity subject to HIPAA can use NIST SP 800-66 to strengthen and demonstrate compliance with the Security Rule.

NIST SP 800-66 provides technical guidance and control recommendations that support the requirements of the HIPAA Security Rule, translating legal standards into practical IT and risk management processes.

The framework focuses on safeguarding electronic protected health information (ePHI), such as patient records, lab results, prescriptions, and other identifiable health data stored or transmitted electronically.

It gives covered entities a structured yet flexible approach to identifying threats, assessing vulnerabilities, and implementing appropriate safeguards for ePHI—core requirements under HIPAA.

Yes—business associates that create, receive, maintain, or transmit ePHI on behalf of a covered entity can use NIST SP 800-66 to guide their HIPAA compliance efforts.

Failure to protect ePHI may result in HIPAA violations, financial penalties, regulatory investigations, and damage to reputation or patient trust.

SAI360 helps healthcare organizations implement risk-based controls, track HIPAA obligations, and automate assessments to maintain continuous compliance and protect patient data.

Let Us Help

SAI360 enables you to strengthen HIPAA compliance with real-time insights and automation tools to:

  • Protect electronic protected health information

  • Align controls with NIST SP 800-66 guidance

  • Simplify risk and compliance workflows